Skip Navigation

DNA Research 1996 3(3):157-164; doi:10.1093/dnares/3.3.157
© 1996 by Kazusa DNA Research Institute
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Request Permissions
Google Scholar
Right arrow Articles by Korotkov, E. V.
Right arrow Articles by Korotkova, M. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Korotkov, E. V.
Right arrow Articles by Korotkova, M. A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Enlarged Similarity of Nucleic Acid Sequences

E. V. Korotkov and M. A. Korotkova

117312, Bioengineering Center, Russian Academy of Sciences 60 Oktybrya prospect, 7/1, Moscow, Russia and Department of Cybernetics, Moscow Physical Engineering Institute 115409, Kashirskoe chosse, 31, Moscow, Russia

* To whom correspondence should be addressed. Tel. +7-095-430-32-70, Fax. +7-095-135-05-71, E-mail: korotkov{at}biengi.msk.su

The concept of nucleic acid sequence base alternations is presented. The number of base alterations for the sequences of different length is established. The definition of "enlarged similarity" of nucleic acids sequences on the basis of sequence base alterations is introduced. Mutual information between sequences is used as a quantitative measure of enlarged similarity for two compared sequences. The method of mutual information calculation is developed considering the correlation of bases in compared sequences. The definitions of correlated similarity and evolution similarity between compared sequences are given. Results of the use of enlarged similarity approach for DNA sequences analysis are discussed.

Key words: DNA sequence; computer analysis; sequence base alteration; mutual information; enlarged similarity


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.